Sphinganine

We provide MS-based lipid analysis of dhSph sphingolipids in a variety of sample types and deliver results in six or less weeks.
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Details

Sphingolipids
Lipid Category
Sphingoid Bases
Lipid Group
Sphinganine
Lipid Class

About the structure and biological function of dhSph

What is the structure of Sphinganine?

Sphinganines (dihydrosphingosines, D-erythro-sphinganines, or dhSph) belong to the group of sphingoid bases within the sphingolipids. Their structure consists of an amino alcohol with a saturated hydrocarbon chain.

What is the function of Sphinganine?

Sphinganines serve an important biological function as biosynthetic precursors to sphingosine and thus more complex sphingolipids. Little is known about the cell biological function of free sphinganines aside their difference from sphingosines. However, it has been linked to sleep apnea and sepsis. Additionally, some fungi produce sphinganine analog mycotoxins to disrupt sphingolipid metabolism in plants.

Sphinganine lipidomics analysis with Lipotype

Structural details
Variants identified
Approach
Method mass spectrometry
Device
Quantification yes
Delivery time
Lipidomics data pmol & mol%
Figures yes

Example Structure
dhSph

An example for the molecular structure of sphinganine, specifically SPB 18:0;O2.

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dhSph
analysis?

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Lipid Navigator

Categories

Fatty AcylsGlycerolipidsPhospholipidsSphingolipidsSterol LipidsPrenol Lipids

Groups

Fatty AcidsFatty AldehydesFatty EstersFatty AmidesHeptadecanoidsOctadecanoidsEicosanoidsDocosanoidsGlycerol EstersEster PhospholipidsEther PhospholipidsDiphospha­tidyl­glycerolsCDP-GlycerolsSphingoid BasesCeramide LipidsCerebrosidesDiglycosyl­ceramidesPhospho­sphingolipidsGangliosidesGlobosidesSulfoglyco­sphingolipidsCholesterol LipidsErgosterol LipidsIsoprenoidsQuinones

Classes

FFABCFASCFAMCFALCFAVLCFAoxiFALWECARNAEoxiHTrEoxiOMEoxiODEoxiOTrEPgdLTTXLXIsoPRvEoxiEDEoxiETrEoxiETEoxiEPEMaRRvDPDoxiDPAoxiDHATAGDAGMAGPAPCPEPGPIPSLPALPCLPELPGLPILPSBMPPC O-PE O-LPC O-LPE O-CLCDP-DAGSphdhSphSphPdhSphPGlcSphGalSphCerCerPdhCerdoxCerEOdSEOSEOPEOHNdSNSNPNHAdSASAPAHHexCerGlcCerGalCerDiHexCerLacCerSMCerPEIPCMIPCM(IP)2CGM1GM2GM3GM4GD1GD2GD3GT1GT2GT3GQ1Gb3Gb4SulfCholCEoxiCholLanoDesmLathErgEEC10TC15TSqeoxiSqeUQ
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