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Phosphatidyl-inositol

We provide MS-based lipid analysis of PI phospholipids in a variety of sample types and deliver results in as little as two weeks.

Details

About the structure and biological function of PI

Structure. Phosphatidylinositols (PtdIns, GPIns, or PI) are a type of glycerophosphoinositols, a class of glycerophospholipids. Their structure consists of a glycerol backbone linked to two fatty acids and a phosphoinositol molecule. The fatty acids can be of variable length, hydroxylated, and contain double bonds.

Function. Phosphatidylinositols are key membrane components and vital to many cellular processes. They are the major source for arachidonic acid for the synthesis of eicosanoids, bioactive lipids with signaling functions in allergy, inflammation, childbirth, pain perception, cell growth, blood pressure, and more. Further, phosphatidylinositols are the precursors to phosphoinositides with further signaling and other functional activities

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GENERAL STRUCTURE
PI

General molecular structure of phosphatidylinositol.

PI lipidomics analysis with
Lipotype

Structural detailssubspecies level
Variants identified > 500
Methodmass spectrometry
DeviceQ Exactive Orbitrap (280.000 Res)
Quantificationyes
Delivery time2-6 weeks
Lipidomics datapmol & mol%
Figuresincluded
1Cells Basic includes:
TAG, DAG, PA, PC, PE, PG, PI, PS, CE, SM

2Blood Basic includes:
TAG, DAG, PC, PE, PI, LPC, LPE, Cer, Chol, CE, PC O-, PE O-, SM

REPORTED AS
PI 18:0;0_22:6;0

An example for the molecular structure of phosphatidylinositol, specifically PI 18:0;0_22:6;0.

GENERAL STRUCTURE
PI

General molecular structure of phosphatidylinositol.

REPORTED AS
PI 14:1;0_15:0;0

An example for the molecular structure of phosphatidylinositol, specifically PI 14:1;0_15:0;0.

About Lipotype

Lipotype logo with Claim, 600 dpi

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