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Lyso-phosphatidyl-choline

We provide MS-based lipid analysis of LPC phospholipids in a variety of sample types and deliver results in as little as two weeks.

Details

About the structure and biological function of LPC

Structure. Lyso-phosphatidyl-cholines (lysolecithin, LysoPtdCho, LysoPC, or LPC) are a type of glycerophosphocholines, a class of glycerophospholipids. Their structure consists of a glycerol backbone linked to a fatty acid and a phosphocholine molecule. The fatty acid can be of variable length, hydroxylated, and contain double bonds.

Function. Lyso-phosphatidyl-cholines are potent signaling molecules and they have many functions related to inflammation and the immune system. They are suggested an important factor for neurodegeneration such as cognitive decline and dementia, and promote demyelination of neurons. Impaired levels of LPCs are also linked to cardiovascular disease and cancers. They have some functions in cell signaling. Further, LPC lipids have beneficial effects by activating macrophages.

GENERAL STRUCTURE
LPC

General molecular structure of lyso-phosphatidylcholine.

LPC lipidomics analysis with
Lipotype

Structural detailsspecies level
Variants identified > 100
Methodmass spectrometry (untargeted)
Quantificationyes
Delivery time2-6 weeks
Lipidomics datapmol & mol%
Figuresincluded
1Cells Extended includes:
LPA, LPC, LPE, LPG, LPI, LPS, Cer, CL, PC O-, PE O-, LPC O-, LPE O-, HexCer

2Blood Basic includes:
TAG, DAG, PC, PE, PI, LPC, LPE, Cer, Chol, CE, PC O-, PE O-, SM

REPORTED AS
LPC 16:0;0

An example for the molecular structure of lyso-phosphatidylcholine, specifically LPC 16:0;0.

GENERAL STRUCTURE
LPC

General molecular structure of lyso-phosphatidylcholine.

REPORTED AS
LPC 22:4;0

An example for the molecular structure of lyso-phosphatidylcholine, specifically LPC 22:4;0.

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