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Diacylglycerol

We provide MS-based lipid analysis of DAG glycerolipids in a variety of sample types and deliver results in as little as two weeks.

Details

About the structure and biological function of DAG

Structure. Diacylglycerols (diglycerides, DAG, or DG) are a type of glycerolipids. Their structure consists of a glycerol backbone linked to two fatty acids. The fatty acids can be of variable length, hydroxylated, and contain double bonds.

Function. Diacylglycerols have different biological functions, of which many depend on the position of the two fatty acids at the glycerol backbone. Thus, diacylglycerols serve as key intermediates in the synthesis of glycerolipids such as glycerophospholipids and triacylglycerols. They can also function in cellular signaling, and their physical properties influence cell membrane biophysics. They are important immunomodulators. Further, diacylglycerols accumulate in many organs in obesity and can be an important factor in cancer.

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GENERAL STRUCTURE
DAG

General molecular structure of diacylglycerol.

DAG lipidomics analysis with
Lipotype

Structural detailssubspecies level
Variants identified > 500
Methodmass spectrometry
DeviceQ Exactive Orbitrap (280.000 Res)
Quantificationyes
Delivery time2-6 weeks
Lipidomics datapmol & mol%
Figuresincluded
1Cells Basic includes:
TAG, DAG, PA, PC, PE, PG, PI, PS, CE, SM

2Blood Basic includes:
TAG, DAG, PC, PE, PI, LPC, LPE, PC O-, PE O-, Chol, CE, Cer, SM

3Skin includes:
TAG, DAG, Chol, CE, AdS, AS, AP, AH, NdS, NS, NP, NH, EOdS, EOS, EOP, EOH

REPORTED AS
DAG 18:0;0_20:5;0

An example for the molecular structure of diacylglycerol, specifically DAG 18:0;0_20:5;0.

GENERAL STRUCTURE
DAG

General molecular structure of diacylglycerol.

REPORTED AS
DAG 12:0;0_18:2;0

An example for the molecular structure of diacylglycerol, specifically DAG 12:0;0_18:2;0.

About Lipotype

Lipotype logo with Claim, 600 dpi

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