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Cholesteryl esters
We provide MS-based lipid analysis of CE sterol lipids in a variety of sample types and deliver results in as little as two weeks.
Details
About the structure and biological function of CE
Structure. Cholesteryl esters (cholesterol esters, or CE) are a type of sterol lipids. Their structure consists of cholesterol where an ester bond is formed between the hydroxyl group of the steroid structure and a fatty acid. The fatty acid can be of variable length, hydroxylated, and contain double bonds.
Cholesteryl esters are mainly found in animal blood plasma and cells. On a subcellular level, they are enriched in cellular lipid droplets.
Function. Cholesteryl esters function as a transport form of cholesterol in blood plasma and in cells in lipid droplets. They serve as storage containers to buffer excess cholesterol. They also serve as pool for cholesterol, for example for hormone synthesis in the adrenal glands, but also for free fatty acids. Cholesteryl esters accumulate in fatty lesions of atherosclerotic plaques. Further, cholesterol is inefficiently converted to cholesteryl esters in the blood of cardiovascular disease patients.
GENERAL STRUCTURECE
CE lipidomics analysis with
Structural details species level Variants identified > 50 Method mass spectrometry Device Q Exactive Orbitrap (280.000 Res) Quantification yes Delivery time 2-6 weeks Lipidomics data pmol & mol% Figures included
1 Cells Basic includes:2 Blood Basic includes:3 Skin includes:
REPORTED ASCE 16:4;0
GENERAL STRUCTURECE
REPORTED ASCE 16:2;0
About Lipotype
Lipotype is the leading lipidomics service provider for industry and academia. Order your service, send your samples, get your data.
