Cholesteryl esters are a key class of cholesterol-based lipids, playing essential roles in cholesterol transport and storage.
Cholesteryl esters act as a transport form of cholesterol in both blood plasma and within cells, primarily stored in lipid droplets. They serve as a crucial buffer for excess cholesterol and provide a ready reservoir for cholesterol-dependent processes such as hormone synthesis.
Cholesteryl esters are also clinically significant. For example, they accumulate in atherosclerotic plaques. Cholesterol is inefficiently converted to cholesteryl esters in the blood of cardiovascular disease patients.
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