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CDP-diacylglycerol

CDP-diacylglycerol

We provide MS-based lipid analysis of CDP-DAG phospholipids in a variety of sample types and deliver results in as little as two weeks.

Details

Phospholipids
Lipid Category
CDP-Glycerols
Lipid Group

About the structure and biological function of CDP-diacylglycerol

About the structure and biological function of CDP-DAG

Structure. CDP-diacylglycerols (cytidine-diphosphate-diglycerides, CDP-diglycerides, or CDP-DAG) belong to the group of CDP-glycerols within the phospholipids. Their structure consists of a glycerol backbone linked to two fatty acids and a cytidine diphosphate molecule (CDP). The fatty acids can be of variable length, hydroxylated, and contain double bonds.

Function. CDP-DAG lipids occupy a branch point in the biosynthesis of complex glycerolipids. The distinct end-products depend on the subcellular location of synthesis. For example, CDP-DAGs are used for cardiolipin biosynthesis in mitochondria and for phosphatidylinositol and phosphatidylglycerol synthesis in the endoplasmic reticulum. Thus, CDP-DAG lipids also have a key role in regulation of phosphatidylinositol signal transduction. Further, they are linked to lipid droplet size in adipocytes.

CDP-diacylglycerol lipidomics analysis with Lipotype

Covered classes0
Approachuntargeted
Method
DeviceQ Exactive Orbitrap (280.000 Res)
Quantification
Delivery time2-4 weeks
Lipidomics data
Figuresincluded

STRUCTURE
CDP-diacylglycerol

CDP-diacylglycerol

ABOUT LIPOTYPE

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Lipotype is the leading lipidomics service provider for industry and academia. Order your service, send your samples, get your data.

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Cardiolipin

Cardiolipin

We provide MS-based lipid analysis of CL phospholipids in a variety of sample types and deliver results in as little as two weeks.

Details

Phospholipids
Lipid Category
Cardiolipin
Lipid Class

About the structure and biological function of Cardiolipin

About the structure and biological function of CL

Structure. Cardiolipins (Ptd2Gro, or CL) belong to the group of diphosphatidylglycerols within the phospholipids. Their structure consists of two diacylglycerophosphates linked to each other via a third glycerol backbone. In total, cardiolipins contain four ester-linked fatty acids. They can be of variable length, hydroxylated, and contain double bonds.

Function. Cardiolipins are tied to the synthesis of ATP, cellular energy. They are a vital component of cellular membranes whose function is to generate an electrochemical potential, such as mitochondrial membranes. There, they interact with many membrane proteins regulating and controlling their functions. They are also involved in apoptosis and mitophagy, programmed cell death and mitochondrial degradation. Further, cardiolipin aberrations are linked to Barth syndrome, cancer, diabetes, and Parkinson’s disease.

Cardiolipin lipidomics analysis with Lipotype

Covered classes0
Approachuntargeted
Method
DeviceQ Exactive Orbitrap (280.000 Res)
Quantification
Delivery time2-6 weeks
Lipidomics data
Figuresincluded

ABOUT LIPOTYPE

Lipotype logo with Claim, 600 dpi

Lipotype is the leading lipidomics service provider for industry and academia. Order your service, send your samples, get your data.

Request analysis

You want to inquire lipid analysis for your project or ask questions about Lipotype Lipidomics? Please use the contact form below!

read more ➔

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Lyso-phosphatidyl­serine

Lyso-phosphatidyl­serine

We provide MS-based lipid analysis of LPS phospholipids in a variety of sample types and deliver results in as little as two weeks.

Details

Phospholipids
Lipid Category

About the structure and biological function of Lyso-phosphatidyl­serine

About the structure and biological function of LPS

Structure. Lyso-phosphatidyl-serines (LysoPtdSer, LysoPS, or LPS) belong to the group of ester phospholipids within the phospholipids. Their structure consists of a glycerol backbone linked to a fatty acid and a phosphoserine molecule. The fatty acid can be of variable length, hydroxylated, and contain double bonds.

Function. Lyso-phosphatidyl-serines are mediators in many biological processes, especially those of the immune system of animals. LPS levels are elevated by various inflammatory stimuli and after injury, where it can transmit the information to other cells. Thus they contribute to the resolution of inflammation. Yet, certain LPS lipids have pro-inflammatory reactions. Further, LPS metabolism aberrations are linked to cancers, night blindness, and PHARC, a genetic neurological disorder.

Lyso-phosphatidyl­serine lipidomics analysis with Lipotype

Covered classes0
Approachuntargeted
Method
DeviceQ Exactive Orbitrap (280.000 Res)
Quantification
Delivery time2-6 weeks
Lipidomics data
Figuresincluded

ABOUT LIPOTYPE

Lipotype logo with Claim, 600 dpi

Lipotype is the leading lipidomics service provider for industry and academia. Order your service, send your samples, get your data.

Request analysis

You want to inquire lipid analysis for your project or ask questions about Lipotype Lipidomics? Please use the contact form below!

read more ➔

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Lyso-phosphatidyl­inositol

Lyso-phosphatidyl­inositol

We provide MS-based lipid analysis of LPI phospholipids in a variety of sample types and deliver results in as little as two weeks.

Details

Phospholipids
Lipid Category

About the structure and biological function of Lyso-phosphatidyl­inositol

About the structure and biological function of LPI

Structure. Lyso-phosphatidyl-inositols (LysoPtdIns, LysoPI, or LPI) belong to the group of ester phospholipids within the phospholipids. Their structure consists of a glycerol backbone linked to a fatty acid and a phosphoinositol molecule. The fatty acid can be of variable length, hydroxylated, and contain double bonds.

Function. Lyso-phosphatidyl-inositols are intermediates in the remodeling of phosphatidylinositols, such as the release of arachidonic acid for eicosanoid biosynthesis. Yet, LPI lipids possess signaling functions on their own. They interact with receptors and stimulate the release of hormones from the pancreas for the regulation of glucose uptake. LPI levels are elevated in highly proliferative cancer cells and serve as biomarkers for poor prognosis in cancer patients. Further, LPIs together with other lysophospholids, are linked to a number of metabolic diseases such as obesity.

Lyso-phosphatidyl­inositol lipidomics analysis with Lipotype

Covered classes0
Approachuntargeted
Method
DeviceQ Exactive Orbitrap (280.000 Res)
Quantification
Delivery time2-6 weeks
Lipidomics data
Figuresincluded

ABOUT LIPOTYPE

Lipotype logo with Claim, 600 dpi

Lipotype is the leading lipidomics service provider for industry and academia. Order your service, send your samples, get your data.

Request analysis

You want to inquire lipid analysis for your project or ask questions about Lipotype Lipidomics? Please use the contact form below!

read more ➔

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Lyso-phosphatidyl­glycerol

Lyso-phosphatidyl­glycerol

We provide MS-based lipid analysis of LPG phospholipids in a variety of sample types and deliver results in as little as two weeks.

Details

Phospholipids
Lipid Category

About the structure and biological function of Lyso-phosphatidyl­glycerol

About the structure and biological function of LPG

Structure. Lyso-phosphatidyl-glycerols (LysoPtdGro, LysoPG, or LPG) belong to the group of ester phospholipids within the phospholipids. Their structure consists of a glycerol backbone linked to a fatty acid and a phosphoglycerol molecule. The fatty acid can be of variable length, hydroxylated, and contain double bonds.

Function. Little is known about the function of lyso-phosphatidyl-glycerols in animals. Elevated LPG levels have been detected in acute coronary syndrome and they may be linked to cardiovascular diseases. In bacteria, LPGs are the lipid backbone elements of lipopolysaccharides, structural components of the bacterial capsule which are important virulence factors for many pathogens. Further, LPG lipids serve as precursors for phosphatidylglycerols.

Lyso-phosphatidyl­glycerol lipidomics analysis with Lipotype

Covered classes0
Approachuntargeted
Method
DeviceQ Exactive Orbitrap (280.000 Res)
Quantification
Delivery time2-6 weeks
Lipidomics data
Figuresincluded

STRUCTURE
Lyso-phosphatidyl­glycerol

Lyso-phosphatidyl­glycerol

ABOUT LIPOTYPE

Lipotype logo with Claim, 600 dpi

Lipotype is the leading lipidomics service provider for industry and academia. Order your service, send your samples, get your data.

Request analysis

You want to inquire lipid analysis for your project or ask questions about Lipotype Lipidomics? Please use the contact form below!

read more ➔

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Lyso-phosphatidyl­ethanolamine

Lyso-phosphatidyl­ethanolamine

We provide MS-based lipid analysis of LPE phospholipids in a variety of sample types and deliver results in as little as two weeks.

About the structure and biological function of Lyso-phosphatidyl­ethanolamine

About the structure and biological function of LPE

Structure. Lyso-phosphatidyl-ethanolamines (lysocephalins, LysoPtdEtn, LysoPE, or LPE) belong to the group of ester phospholipids within the phospholipids. Their structure consists of a glycerol backbone linked to a fatty acid and a phosphoethanolamine molecule. The fatty acid can be of variable length, hydroxylated, and contain double bonds.

Function. Lyso-phosphatidyl-ethanolamines are involved in cellular processes such as differentiation and migration of certain neuronal cells, but also of various cancer cells. In plants, LPEs function as inhibitors for a key enzyme in membrane lipid degradation, thus retarding senescence of leaves, flowers, and fruits. They are used commercially to stimulate ripening and extend shelf-life of fruit, and increase vase life of cut flowers. Further, LPE lipids serve as precursors for phosphatidyl-ethanolamines.

Lyso-phosphatidyl­ethanolamine lipidomics analysis with Lipotype

Covered classes0
Approachuntargeted
Method
DeviceQ Exactive Orbitrap (280.000 Res)
Quantification
Delivery time2-6 weeks
Lipidomics data
Figuresincluded

ABOUT LIPOTYPE

Lipotype logo with Claim, 600 dpi

Lipotype is the leading lipidomics service provider for industry and academia. Order your service, send your samples, get your data.

Request analysis

You want to inquire lipid analysis for your project or ask questions about Lipotype Lipidomics? Please use the contact form below!

read more ➔

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Lyso-phosphatidyl­choline

Lyso-phosphatidyl­choline

We provide MS-based lipid analysis of LPC phospholipids in a variety of sample types and deliver results in as little as two weeks.

Details

Phospholipids
Lipid Category

About the structure and biological function of Lyso-phosphatidyl­choline

About the structure and biological function of LPC

Structure. Lyso-phosphatidyl-cholines (lysolecithin, LysoPtdCho, LysoPC, or LPC) belong to the group of ester phospholipids within the phospholipids. Their structure consists of a glycerol backbone linked to a fatty acid and a phosphocholine molecule. The fatty acid can be of variable length, hydroxylated, and contain double bonds.

Function. Lyso-phosphatidyl-cholines are potent signaling molecules and they have many functions related to inflammation and the immune system. They are suggested an important factor for neurodegeneration such as cognitive decline and dementia, and promote demyelination of neurons. Impaired levels of LPCs are also linked to cardiovascular disease and cancers. They have some functions in cell signaling. Further, LPC lipids have beneficial effects by activating macrophages.

Lyso-phosphatidyl­choline lipidomics analysis with Lipotype

Covered classes0
Approachuntargeted
Method
DeviceQ Exactive Orbitrap (280.000 Res)
Quantification
Delivery time2-6 weeks
Lipidomics data
Figuresincluded

ABOUT LIPOTYPE

Lipotype logo with Claim, 600 dpi

Lipotype is the leading lipidomics service provider for industry and academia. Order your service, send your samples, get your data.

Request analysis

You want to inquire lipid analysis for your project or ask questions about Lipotype Lipidomics? Please use the contact form below!

read more ➔

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Lyso-phosphatidate

Lyso-phosphatidate

We provide MS-based lipid analysis of LPA phospholipids in a variety of sample types and deliver results in as little as two weeks.

Details

Phospholipids
Lipid Category

About the structure and biological function of Lyso-phosphatidate

About the structure and biological function of LPA

Structure. Lyso-phosphatidates (lyso-phosphatidic acids, LysoPtdOH, LysoPA, or LPA) belong to the group of ester phospholipids within the phospholipids. Their structure consists of a glycerol backbone linked to a fatty acid and a phosphate group. The fatty acid can be of variable length, hydroxylated, and contain double bonds.

Function. Lyso-phosphatidates influence many biochemical processes in cells and act as lipid mediators with growth factor-like activities. They act upon nearly all cell types, often as signal for proliferation, cytoskeleton re-arrangement, cell differentiation, cytokine secretion, and many other vital cellular processes. Further, there is evidence for the role of LPA lipids in the remodeling of lipid metabolism in cancer. They are a target of pharmaceutical research in the search for new cancer drugs.

Lyso-phosphatidate lipidomics analysis with Lipotype

Covered classes0
Approachuntargeted
Method
DeviceQ Exactive Orbitrap (280.000 Res)
Quantification
Delivery time2-6 weeks
Lipidomics data
Figuresincluded

STRUCTURE
Lyso-phosphatidate

Lyso-phosphatidate