Oxidized octadecadienoic acids belong to the group of octadecanoids within the fatty acyls. Their structure is based on octadecanoic acid, an eighteen carbon atoms long hydrocarbon chain with a carboxyl group. The chain contains two double bonds, from which their name derives. Oxidized octadecadienoic acids may contain multiple oxygen containing substituents.
Oxidized octadecadienoic acids are associated with inflammation. They activate receptors inducing pro-inflammatory cytokines, contribute to pain perception and serve as markers for oxidative stress. While they may trigger programmed cell death in some cancers, elevated levels of oxidized octadecadienoic acids have been found in psoriasis and non-alcoholic steatohepatitis.
Here you can read more about the analysis of oxidized octadecadienoic acids performed at Lipotype:
#FattyAcyls #lipid #lipidomics #MassSpectrometry #OxidizedOctadecaenoicAcid
