A quick introduction to Lipidomics.
Building blocks of life
There are thousands of distinct lipid molecules. Each of them is chemically different and thus, lipids have many different biological functions. Their main function is to form the matrix of our cell membranes where they support a variety of functions essential for life. But lipids also store energy, they serve as hormones and signalling molecules.
Lipidomics is the study of lipids and lipid metabolites in biological systems – the metabolomics science of lipids.
Lipids in health and disease
Recent studies have demonstrated that lipids are not only involved in cardiovascular disease (cholesterol!) and obesity, but they also play an important role in Alzheimer’s disease, asthma, diabetes, and hypertension. The task of lipidomics is to identify the lipid molecules concerned. Like sequencing DNA in genomics, lipidomics has developed technology to analyse the lipid composition in cells and body fluids.
Lipidomics is not only interesting for basic research and clinical diagnostics. It can also be used to develop functional food and nutraceuticals or to test cosmetic products dermatologically. However, until now lipidomics was time-consuming, work-intensive or not detailed enough to do a good job.
Lipotype Shotgun Lipidomics
We live in exciting times. Technological progress made it possible to analyse lipids with unprecedented precision.
Based on many years of research by the laboratories of professor Kai Simons and Dr Andrej Shevchenko, Lipotype was founded and shotgun mass spectrometry was developed to analyse hundreds of lipids in only a few minutes with absolute quantification.
This effective routine of Lipotype Shotgun Lipidomics became possible by introducing a unique workflow that combined improved extraction protocols with cutting edge mass spectrometry and proprietary software. Our interdisciplinary team has experts in biology, chemistry, robotics and informatics, all trained at the Max Planck Institute in Dresden with several years of lipid experience and this is unique world-wide!
The future is today
The quality of Lipotype Shotgun Lipidomics makes it possible to identify clinically relevant biomarkers on a scale that is unprecedented. This is the basis for novel optimized products in different areas, including multi-parameter diagnostics, drug development, nutrition, cosmetics or industrial biotechnology.
Our services provide unrivaled tools for our clients to develop products with a significant competitive edge.
See our services!
One more thing!
What else makes Lipotype unique? We are the world champions in lipid rafting! What does this mean? Our cell membranes are full of nano scale rafts, which float around in the lipid bilayer and function as platforms in many cellular processes. This is one reason why we need cholesterol because rafts are glued together by cholesterol.
We envisage rafts as key elements in human diseases.