
The lipid composition of human skin is essential for skin function. However, the simultaneous quantification of a wide range of stratum corneum and sebaceous lipids is not trivial. We developed and validated a quantitative high-throughput shotgun mass spectrometry-based platform for lipid analysis of skin samples (Sadowski T. et al. “Large-scale human skin lipidomics by quantitative, high-throughput shotgun mass spectrometry.” Scientific Reports 2017, doi: 10.1038/srep43761)
Learn more about Lipotype Skin Lipidomics. Our White Paper highlights a novel skin lipid analysis platform for topical drug development, cosmetic claim support and development of personalized cosmetics. It includes:
- Latest technological advancements in shotgun mass spectrometry for skin lipidomics;
- Large lipidomic study of 268 samples in total;
- Investigation of the relationship between sampling depth and lipid composition;
- Lipidome variability in samples from 14 different sampling sites on the human body;
- Assessment of the impact of age and sex on lipidome in 104 healthy subjects.
Discover the free White Paper about Lipotype Skin Lipidomics. Just fill out the form!
ADVANTAGES OF
LIPOTYPE SKIN LIPIDOMICS
WIDE COVERAGE
- Covering 12 ceramide subclasses, tri- and diacylglycerol, cholesterol, cholesterol ester
- 250 individual lipid species per sample
FULL HIGH-THROUGHPUT
- Cutting-edge mass spectrometry, automated sample extraction, processing and data analysis
- 100 skin samples per day
- 2 weeks turnaround time
ABSOLUTE QUANTIFICATION
- Qualification via internal standards
- Results in mol% and pmol
- Technical variation <10%
EASY SAYMPLING VIA TAPE-STRIPPING
- Reproducible
- Controlled sampling site
in all planes - Non-invasive
but society demands something more than this«
Mark Twain