The lipid composition of human skin is essential for skin function. However, the simultaneous quantification of a wide range of stratum corneum and sebaceous lipids is not trivial. We developed and validated a quantitative high-throughput shotgun mass spectrometry-based platform for lipid analysis of skin samples (Sadowski T. et al. “Large-scale human skin lipidomics by quantitative, high-throughput shotgun mass spectrometry.” Scientific Reports 2017, doi: 10.1038/srep43761)

 

Learn more about Lipotype Skin Lipidomics. Our White Paper highlights a novel skin lipid analysis platform for topical drug development, cosmetic claim support and development of personalized cosmetics. It includes:

  • Latest technological advancements in shotgun mass spectrometry for skin lipidomics;
  • Large lipidomic study of 268 samples in total;
  • Investigation of the relationship between sampling depth and lipid composition;
  • Lipidome variability in samples from 14 different sampling sites on the human body;
  • Assessment of the impact of age and sex on lipidome in 104 healthy subjects.

Discover the free White Paper about Lipotype Skin Lipidomics. Just fill out the form!

 

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ADVANTAGES OF
LIPOTYPE SKIN LIPIDOMICS

 

WIDE COVERAGE

  • Covering 12 ceramide subclasses, tri- and diacylglycerol, cholesterol, cholesterol ester
  • 250 individual lipid species per sample

FULL HIGH-THROUGHPUT

  • Cutting-edge mass spectrometry, automated sample extraction, processing and data analysis
  • 100 skin samples per day
  • 2 weeks turnaround time

ABSOLUTE QUANTIFICATION

  • Qualification via internal standards
  • Results in mol% and pmol
  • Technical variation <10%

EASY SAYMPLING VIA TAPE-STRIPPING

  • Reproducible
  • Controlled sampling site
    in all planes
  • Non-invasive
»The finest clothing made is a person’s own skin,
but society demands something more than this«
Mark Twain

About Lipotype

 
Lipotype is a spin-off company from the Kai Simons and Andrej Shevchenko labs of the world-renowned Max-Planck-Institute of Molecular Cell Biology and Genetics in Dresden, Germany. Drawing on many years of cutting edge research experience, Lipotype delivers comprehensive, absolutely quantitative lipid analysis services for clinical and biological samples on a high-throughput scale. Lipotype offers high quality lipid analysis services for a wide range of customers and applications including biomarker identification for clinical researchers, pharma and biotech companies, functional food development for the food industry, claim support for the cosmetics industry, as well as for the small-scale profiling needs of academic researchers.