Highlights of our unique

LIPID ANALYSIS SERVICES

for a wide range of customers and applications

Lipotype offers unique lipid analysis services from organelles, microorganisms, cultured cells to tissues and organs. The advantages are such as broad coverage of lipids (>2300 absolutely quantified lipids), small sample amounts (e.g. 100.000 cells), two weeks delivery time of results, comprehensive statistical analysis and graphical presentation of data.

Lipotype Coverage

ULTRA-BROAD COVERAGE OF LIPIDS

Lipotype Shotgun Lipidomics Technology provides a broad coverage of membrane lipids, but also of storage lipids. Our analysis routinely covers 30 different lipid classes (e.g. TAG or PC) on the level of lipid species (e.g. TAG 54:0) or subspecies (e.g. PC 18:0_16:0, including the fatty acid information) – in total more than 2300 individual lipids.  Moreover our platform allows for the analysis of various sample types – from organelles, bacteria, yeast and other microorganisms, cultured cells and blood plasma to tissues and organs: muscles, liver, brain, and many others. The crucial point: while our technology supports a wide range of sample types it requires only minimal amounts of sample amounts per analysis, e.g. 15 µl or less of blood plasma.

Full High Troughput

FULL HIGH-THROUGHPUT

Lipotype uses Shotgun Lipidomics Technology without time-consuming chromatographic separation of lipids before analysis. We utilize the advantages of cutting-edge mass spectrometry, combined with automated sample extraction, processing and data analysis. In this way, our exquisitely standardized platform allows for the analysis of hundreds of samples per day, offering unprecedented delivery time of weeks instead months for complete results and associated reports.

Absolute Quantification

ABSOLUTE QUANTIFICATION

The quantification is achieved using lipid class-specific internal standards that allow for unbiased and direct quantitation of individual lipids directly from their mass spectra intensities. Therefore, we deliver results expressed in absolute and not in relative values, which provides the basis for a direct comparison of different samples and experiments.

Lipidomics with highest quality

HIGHEST QUALITY

Lipotype Shotgun Lipidomics Technology is highly reproducible1, 2, robust and reliable. This performance is ensured by a rigorous quality control system. The high standards of Lipotype operations are based on years of research experience on lipids and lipidomics technology. This is reflected in numerous scientific publications from different fields, as well as in industry-oriented applications and patents.

Lipid Identification

INNOVATIVE LIPID IDENTIFICATION:
LIPOTYPEXPLORER

Lipotype uses proprietary software for lipid identification: LipotypeXplorer. With the molecular fragmentation query language (MFQL) it identifies lipids with high precision and without bias. LipotypeXplorer does not rely on predefined databases, which have to be curated and maintained and which might not be complete.

analyze lipid classes and fatty acid saturation

NEW LEVEL OF DATA ANALYSIS

Lipidomes have an inherent structure (e.g. lipid classes and fatty acid saturation) that is accessed by multiple layers of dynamic aggregation. With Lipotype Zoom your data can be viewed and downloaded in graphs, heat maps and principle component analysis plots. Moreover, our advanced statistical reports supply you with customized cohort comparisons, correlation and pathway enrichment analyses. We empower you to interpret your data to always be one step ahead.

Experts in Cell biology, Bioinformatics, lipidomics

PERSONAL APPROACH

We are scientists too, and we know that with each experiment new queries pop up. And as we are experts in membrane and lipid biology and chemistry, mass spectrometry, and bioinformatics originating from the world-renowned Max Planck Institute of Molecular Cell Biology and Genetics in Dresden, Germany, you can benefit from our experience in lipidomics and cell biology as well as bioinformatics by means of personal consultations from sample preparation to interpretation of results.

Reasonable Prices by high-throughput

REASONABLE PRICES

Lipotype Shotgun Lipidomics is a high-throughput lipid analysis. The decreased processing time and increased sample numbers together with small samples amounts required for an analysis, turn into a cost advantage for you. We want you to profit from our innovation by offering reasonable prices that make lipidomics an affordable tool in your research projects.

Coverage of Lipids

Animal and yeast Samples

Basic Coverage

 

PA

phosphatidate

PC

phosphatidylcholine

PE

phosphatidylethanolamine

PG

phosphatidylglycerol

PI

phosphatidylinositol

PS

phosphatidylserine

DAG

diacylglycerol

TAG

triacylglycerol

SM

sphingomyelin

CE

cholesteryl ester

EE

ergosteryl estery

Extended Coverage

 

LPA

lyso-phosphatidate

LPC

lyso-phosphatidylcholine

LPE

lyso-phosphatidylethanolamine

LPG

lyso-phosphatidylglycerol

LPI

lyso-phosphatidylinositol

LPS

lyso-phosphatidylserine

PC O-

ether-linked PC

PE O-

ether-linked PE

LPC O-

ether-linked LPC

LPE O-

ether-linked LPE

CER

ceramide

HEXCER

hexosylceramide

CL

cardiolipin

yeast specific coverage

 

IPC

inositolphosphorylceramide

MIPC

mannosyl-inositol phosphorylceramide

M(IP)2C

mannosyl-di-(inositolphosphoryl) ceramide

CDP-DAG

CDP-diacylglycerol

animals
y yeast


Blood Plasma Samples

Basic Coverage

 

PC

phosphatidylcholine

PE

phosphatidylethanolamine

PI

phosphatidylinositol

DAG

diacylglycerol

TAG

triacylglycerol

SM

sphingomyelin

CHOL

free cholesterol

CE

cholesteryl ester

CER

ceramide

LPC

lyso-phosphatidylcholine

LPE

lyso-phosphatidylethanolamine

PC O-

ether-linked PC

PE O-

ether-linked PE

Extended Coverage

 

PA

phosphatidate

PG

phosphatidylglycerol

PS

phosphatidylserine

LPA

lyso-phosphatidate

LPI

lyso-phosphatidylinositol

LPS

lyso-phosphatidylserine

LPC O-

ether-linked LPC

LPE O-

ether-linked LPE

HEXCER

hexosyl ceramide