We provide MS-based lipid analysis of EOCer skin ceramides in a variety of skin sample types and deliver results in as little as three weeks.


Lipid Category
Ceramide Lipids
Lipid Group

About the structure and biological function of EOCer

Structure. Omega-hydroxyceramides (EOCer) belong to the group of ceramide lipids within the sphingolipids. Their structure consists of a sphingoid base and a fatty acid. The fatty acid is an ω-hydroxy fatty acid and “elongated” by a further fatty acid via an ester bond. The fatty acid can be of variable length, contain hydroxyl groups, and encompass multiple double bonds.

Function. The biological function of omega-hydroxyceramides mostly revolves around skin health, where they serve mainly structural roles. EOCer ceramides are critical to the formation of the lamellar phase of the epidermal barrier which prevents trans-epidermal water loss but also protects from the environment. Aberrations of skin ceramide levels can contribute or lead to skin conditions. In general, reduced levels of omega-hydroxyceramides are linked to dry skin and psoriasis.

EOCer lipidomics analysis with

Structural detailsspecies level
Noted subclassesEOdS, EOS, EOP, EOH
Variants identified > 50
Methodmass spectrometry
DeviceQ Exactive Orbitrap (280.000 Res)
Delivery time3-6 weeks
Lipidomics datapmol & mol%


An example for the molecular structure of omega-hydroxy-sphingosines, specifically EOS 65:3;2.


Lipotype logo with Claim, 600 dpi

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