About the structure and biological function of PG
Structure. Phosphatidylglycerols (PtdGro, GPGro, or PG) are a type of glycerophosphoglycerols, a class of glycerophospholipids. Their structure consists of a glycerol backbone linked to two fatty acids and a phosphoglycerol molecule. The fatty acids can be of variable length, hydroxylated, and contain double bonds.
Phosphatidylglycerols are found in all organisms and each cell type but elevated in bacteria. On a subcellular level, they are enriched in the cell membrane.
Function. Phosphatidylglycerols are key intermediates in the biosynthesis of many lipids but especially of cardiolipin. They are essential for the development of normal membranes of chloroplasts and mitochondria in higher plants. In bacteria, phosphatidylglycerols are important for optimal functioning of the bacterial machinery and play a role in protein folding and binding. Further, phosphatidylglycerols have a role in the regulation of the innate immune response in the lungs.
Neurons & Glia Cells
The brain of mammals is the second-most lipid-rich organ. Lipid analysis of neural cells helps understand its complex structure.
PG lipidomics analysis with
|Structural details||subspecies level|
|Variants identified||> 500|
|Device||Q Exactive Orbitrap (280.000 Res)|
|Delivery time||2-6 weeks|
|Lipidomics data||pmol & mol%|
TAG, DAG, PA, PC, PE, PG, PI, PS, CE, SM
2Blood Extended includes:
PA, PG, LPA, LPI, LPC O-, LPE O-, HexCer
Lipotype is the leading lipidomics service provider for industry and academia. Order your service, send your samples, get your data.
You want to inquire lipid analysis for your project or ask questions about Lipotype Shotgun Lipidomics? Please use the contact form below!