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Phosphatidyl-glycerol

We provide MS-based lipid analysis of PG phospholipids in a variety of sample types and deliver results in as little as two weeks.

Details

About the structure and biological function of PG

Structure. Phosphatidylglycerols (PtdGro, GPGro, or PG) are a type of glycerophosphoglycerols, a class of glycerophospholipids. Their structure consists of a glycerol backbone linked to two fatty acids and a phosphoglycerol molecule. The fatty acids can be of variable length, hydroxylated, and contain double bonds.

Function. Phosphatidylglycerols are key intermediates in the biosynthesis of many lipids but especially of cardiolipin. They are essential for the development of normal membranes of chloroplasts and mitochondria in higher plants. In bacteria, phosphatidylglycerols are important for optimal functioning of the bacterial machinery and play a role in protein folding and binding. Further, phosphatidylglycerols have a role in the regulation of the innate immune response in the lungs.

GENERAL STRUCTURE
PG

General molecular structure of phosphatidylglycerol.

PG lipidomics analysis with
Lipotype

Structural detailssubspecies level
Variants identified > 500
Methodmass spectrometry (untargeted)
Quantificationyes
Delivery time2-6 weeks
Lipidomics datapmol & mol%
Figuresincluded
1Cells Basic includes:
TAG, DAG, PA, PC, PE, PG, PI, PS, CE, SM

2Blood Extended includes:
PA, PG, LPA, LPI, LPC O-, LPE O-, HexCer

REPORTED AS
PG 14:1;0_16:0;0

An example for the molecular structure of phosphatidylglycerol, specifically PG 14:1;0_16:0;0.

GENERAL STRUCTURE
PG

General molecular structure of phosphatidylglycerol.

REPORTED AS
PG 18:2;0_22:4;0

An example for the molecular structure of phosphatidylglycerol, specifically PG 18:2;0_22:4;0.

About Lipotype

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