About the structure and biological function of LPE
Structure. Lyso-phosphatidyl-ethanolamines (lysocephalins, LysoPtdEtn, LysoPE, or LPE) are a type of glycerophosphoethanolamines, a class of glycerophospholipids. Their structure consists of a glycerol backbone linked to a fatty acid and a phosphoethanolamine molecule. The fatty acid can be of variable length, hydroxylated, and contain double bonds.
LPE lipids are found in all organisms. On a subcellular level, they are enriched in animal blood plasma and in biological membranes of plants and bacteria.
Function. Lyso-phosphatidyl-ethanolamines are involved in cellular processes such as differentiation and migration of certain neuronal cells, but also of various cancer cells. In plants, LPEs function as inhibitors for a key enzyme in membrane lipid degradation, thus retarding senescence of leaves, flowers, and fruits. They are used commercially to stimulate ripening and extend shelf-life of fruit, and increase vase life of cut flowers. Further, LPE lipids serve as precursors for phosphatidyl-ethanolamines.
LPE lipidomics analysis with
|Structural details||species level|
|Variants identified||> 50|
|Method||mass spectrometry (untargeted)|
|Delivery time||2-6 weeks|
|Lipidomics data||pmol & mol%|
LPA, LPC, LPE, LPG, LPI, LPS, Cer, CL, PC O-, PE O-, LPC O-, LPE O-, HexCer
2Blood Basic includes:
TAG, DAG, PC, PE, PI, LPC, LPE, Cer, Chol, CE, PC O-, PE O-, SM
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