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Ergosteryl ester

We provide MS-based lipid analysis of EE sterols in yeast samples and deliver results in as little as two weeks.

Details

About the structure and biological function of EE

Structure. Ergosteryl esters (ergosterol esters, or EE) are a type of sterol lipids. Their structure consists of ergosterol where an ester bond is formed between the hydroxyl group of the steroid structure and a fatty acid. The fatty acid can be of variable length, hydroxylated, and contain double bonds.

Function. The biological function of ergosteryl esters revolves mainly around ergosterol storage in yeast. During growth retarding conditions but also after fungal death, ergosterol is esterified and stored in cellular lipid droplets. Once esterified, the fatty acids of the ergosteryl esters are not scavenged even during starvation conditions. Further, some ergosteryl esters also show strong growth inhibitory activity against dairy and cosmetic spoilage bacteria.

GENERAL STRUCTURE
EE

General molecular structure of ergosteryl ester.

EE lipidomics analysis with
Lipotype

Structural detailsspecies level
Variants identified > 25
Methodmass spectrometry
DeviceQ Exactive Orbitrap (280.000 Res)
Quantificationyes
Delivery time2-4 weeks
Lipidomics datapmol & mol%
Figuresincluded
1Yeast includes:
CDP-DAG, Erg, EE, IPC, MIPC, M(IP)2C

REPORTED AS
EE 16:1;0

An example for the molecular structure of ergosteryl ester, specifically EE 16:1;0.

GENERAL STRUCTURE
EE

General molecular structure of ergosteryl ester.

REPORTED AS
EE 18:1;0

An example for the molecular structure of ergosteryl ester, specifically EE 18:1;0.

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