Lipidomics Excellence Award
“strengthen life sciences through lipidomics”
LEA, the Lipidomics Excellence Award, has been created to promote, support and strengthen researchers who are eager to contribute to the progress of life sciences through lipidomics.
Up to three individuals with ongoing research are awarded with comprehensive research prizes to support their projects. Applications are open to all researchers who are eager to strengthen life sciences through lipidomics.
The awardees are selected by a panel composed of internationally renown members of academia, each of them recognized as leading experts in their respective fields.
And the winners are…
1. Prize of LEA 2019 goes to…
Prof. Anne-Claude Gavin, Louis-Jeantet Professor at the University of Geneva, has been awarded with the 1. prize for her lipid-transfer research proposal. An emerging player in lipid metabolism and its associated disorders is a group of disease-linked proteins known as lipid-transfer proteins. At least 131 lipid-transfer proteins have been found in humans. Some of them orchestrate the transfer of lipids between membranes, thereby spatially organizing lipids and connecting lipid metabolic pathways. Prof. Anne-Claude Gavin will use her LEA research prize to develop the first molecular cartography of these lipid “highways”. The detailed insights into metabolic signaling and pathways as well as lipid-transfer protein mediated lipid movement, will be integrated into a molecular model to describe cell-specific cancer-associated alterations. This comprehensive model will address multiple fundamental and medically relevant questions.
2. Prize of LEA 2019 is awarded to…
Dr. Oliver Schmidt, Assistant Professor at the Biocenter of the Medical University of Innsbruck, won the 2. prize with his protein degradation research project. To adjust to the ever-changing environment, cells continuously synthesize and degrade proteins. Recently, Dr. Oliver Schmidt together with his colleagues identified a third and new membrane protein degradation pathway in cells, the EGAD pathway. Surprisingly, proteins which are degraded via the EGAD pathway are rich in proteins orchestrating the lipid metabolism. As such, the EGAD pathway is not only involved in protein homeostasis but lipid homeostasis too. Dr. Oliver Schmidt’s research will focus on further investigation and characterization of the influence of the EGAD pathway on lipid metabolism. The findings of this investigation may in future hold the potential to new therapeutic approaches in lipid metabolism associated diseases like diabetes or asthma and might eventually become textbook knowledge.
3. Prize of LEA 2019 was won by…
Prof. Sarah L. Keller, Professor of Chemistry at University of Washington – Seattle, has been awarded with the 3. prize for her proposed cell membrane research project in yeast, an important model organism. When yeast cells switch their stage of growth from proliferation to maintenance, large lipid domains appear in the membrane of their vacuoles, organelles inside the yeast. This change has been linked to the cellular TOR signalling pathway. This pathway is of high importance in humans. For example, the TOR signalling pathway is targeted by rapamycin, a remarkable drug that is applied to inhibit the proliferation of tumor cells and prevent organ rejection in kidney transplant patients. Prof. Sarah Keller will use her LEA research prize to answer questions about what molecular changes in vacuole membranes drive the formation of the lipid domains. Her results will facilitate our understanding of the cell membrane and will serve as a springboard for future investigations.
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With the help of world-leading lipidomics initiatives, LEA is bound to increase lipidomics accessibility in life sciences.
Lipotype, the world leading provider for lipid analysis, strives for scientific excellence and global accessibility of lipidomics. Drawing on many years of research experience and a strong academic history, Lipotype believes and recognizes the urge to support researchers who are eager to contribute to the progress of life sciences. Lipotype founded and organizes LEA to achieve the aspired goals.
LIPID MAPS supports the integrative systems-level analyses of multiomics measurements in human physiology and pathophysiology. They have developed the internationally recognised classification for lipids that is now used by virtually all lipid researchers in the world. The LIPID MAPS Gateway hosts structure drawing tools, informatics/statistics tools, protocols and tutorials. LIPID MAPS supports LEA to strengthen researchers’ lipidomics dimension.
SwissLipids is an expert curated resource that provides a framework for the integration of lipid and lipidomic data with biological knowledge and models. They envision a research atmosphere where deep lipidomic data integration unlocks knowledge. As such, SwissLipids recognizes and supports LEA as an excellent tool to foster research initiative in life sciences through lipidomics.
Forward thinking media aligned themselves with LEA and the mission behind it.