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Ether-linked lyso-phosphatidyl­ethanolamine

Ether-linked lyso-phosphatidyl­ethanolamine

We provide MS-based lipid analysis of LPE O- phospholipids in a variety of sample types and deliver results in as little as two weeks.

About the structure and biological function of Ether-linked lyso-phosphatidyl­ethanolamine

About the structure and biological function of LPE O-

Structure. Ether-linked lyso-phosphatidyl-ethanolamines (LPE O-) belong to the group of ether phospholipids within the phospholipids. Their structure consists of a glycerol backbone linked to a fatty alcohol via an ether bond and a phosphoethanolamine molecule. The fatty acid can be of variable length, hydroxylated, and contain double bonds.

Function. Little is known about the biological function of ether-linked lyso-phosphatidyl-ethanolamines, but they are precursors to ether-linked phosphatidyl-ethanolamines. In the pigmented layer of the human retina that nourishes retinal visual cells, LPE O- lipids are linked to the formation of bisretinoids. Bisretinoids are a family of fluorescent molecules that form in photoreceptor cells and contribute to some retinal diseases, thus LPE O- lipids are suggested to play a role in retinal health.

Ether-linked lyso-phosphatidyl­ethanolamine lipidomics analysis with Lipotype

Covered classes0
Approachuntargeted
Method
DeviceQ Exactive Orbitrap (280.000 Res)
Quantification
Delivery time2-6 weeks
Lipidomics data
Figuresincluded

STRUCTURE
Ether-linked lyso-phosphatidyl­ethanolamine

Ether-linked lyso-phosphatidyl­ethanolamine

ABOUT LIPOTYPE

Lipotype logo with Claim, 600 dpi

Lipotype is the leading lipidomics service provider for industry and academia. Order your service, send your samples, get your data.

Request analysis

You want to inquire lipid analysis for your project or ask questions about Lipotype Lipidomics? Please use the contact form below!

read more ➔

example_structure_of_ether-linked_lyso-phosphatidylcholine_15-0-0.png

Ether-linked lyso-phosphatidyl­choline

Ether-linked lyso-phosphatidyl­choline

We provide MS-based lipid analysis of LPC O- phospholipids in a variety of sample types and deliver results in as little as two weeks.

About the structure and biological function of Ether-linked lyso-phosphatidyl­choline

About the structure and biological function of LPC O-

Structure. Ether-linked lyso-phosphatidyl-cholines (lysoPAF, or LPC O-) belong to the group of ether phospholipids within the phospholipids. Their structure consists of a glycerol backbone linked to a fatty alcohol via an ether bond and a phosphocholine molecule. The fatty acid can be of variable length, hydroxylated, and contain double bonds.

Function. Little is known about the biological function of ether-linked lyso-phosphatidyl-cholines. They are precursors to ether-linked phosphatidylcholines and to platelet activating factor (PAF), which is important for inflammatory reactions but also structure and function of the central nervous system. Elevated levels of LPC O- lipids have been found in patients with Alzheimer’s disease.

Ether-linked lyso-phosphatidyl­choline lipidomics analysis with Lipotype

Covered classes0
Approachuntargeted
Method
DeviceQ Exactive Orbitrap (280.000 Res)
Quantification
Delivery time2-6 weeks
Lipidomics data
Figuresincluded

STRUCTURE
Ether-linked lyso-phosphatidyl­choline

Ether-linked lyso-phosphatidyl­choline

ABOUT LIPOTYPE

Lipotype logo with Claim, 600 dpi

Lipotype is the leading lipidomics service provider for industry and academia. Order your service, send your samples, get your data.

Request analysis

You want to inquire lipid analysis for your project or ask questions about Lipotype Lipidomics? Please use the contact form below!

read more ➔

example_structure_of_ether-linked_phosphatidylethanolamine_18-0-0-22-6-0.png

Ether-linked phosphatidyl­ethanolamine

Ether-linked phosphatidyl­ethanolamine

We provide MS-based lipid analysis of PE O- phospholipids in a variety of sample types and deliver results in as little as two weeks.

About the structure and biological function of Ether-linked phosphatidyl­ethanolamine

About the structure and biological function of PE O-

Structure. Ether-linked phosphatidyl-ethanolamine (plasmanyl-phosphatidyl-ethanolamines, alkyl-phosphatidyl-ethanolamines, or PE O-) belong to the group of ether phospholipids within the phospholipids. Their structure consists of a glycerol backbone linked to a fatty acid, a fatty alcohol and a phosphoethanolamine molecule. One of the fatty acids is bound to the glycerol backbone via an ether bond. The fatty acids can be of variable length, hydroxylated, and contain double bonds.

Function. Ether-linked phosphatidyl-ethanolamines contain high amounts of arachidonic acid required for the biosynthesis of eicosanoids, bioactive lipids with a great role in inflammation. Levels of PE O- lipids are reduced in the blood of patients with multiple sclerosis. That said, elevated levels have been found in cancers, especially in aggressive forms. Further, PE O- lipids are important membrane constituents of neutrophils, the most abundant type of white blood cells in humans.

Ether-linked phosphatidyl­ethanolamine lipidomics analysis with Lipotype

Covered classes0
Approachuntargeted
Method
DeviceQ Exactive Orbitrap (280.000 Res)
Quantification
Delivery time2-6 weeks
Lipidomics data
Figuresincluded

ABOUT LIPOTYPE

Lipotype logo with Claim, 600 dpi

Lipotype is the leading lipidomics service provider for industry and academia. Order your service, send your samples, get your data.

Request analysis

You want to inquire lipid analysis for your project or ask questions about Lipotype Lipidomics? Please use the contact form below!

read more ➔

example_structure_of_ether-linked_phosphatidylcholine_18-1-0-16-0-0.png

Ether-linked phosphatidyl­choline

Ether-linked phosphatidyl­choline

We provide MS-based lipid analysis of PC O- phospholipids in a variety of sample types and deliver results in as little as two weeks.

About the structure and biological function of Ether-linked phosphatidyl­choline

About the structure and biological function of PC O-

Structure. Ether-linked phosphatidyl-cholines (plasmanyl-phosphatidylcholines, alkyl-phosphatidylcholines, Platelet Activating Factor, PAF, or PC O-) belong to the group of ether phospholipids within the phospholipids. Their structure consists of a glycerol backbone linked to a fatty acid, a fatty alcohol and a phosphocholine molecule. One of the fatty acids is bound to the glycerol backbone via an ether bond. The fatty acids can be of variable length, hydroxylated, and contain double bonds.

Function. Ether-linked phosphatidyl-cholines contain high amounts of arachidonic acid required for the biosynthesis of eicosanoids, bioactive lipids with a great role in inflammation. Levels of PC O- lipids are reduced in the blood of patients with multiple sclerosis. On the other hand, elevated levels have been found in cancers, especially in aggressive forms. Further, PC O- lipids are important membrane constituents of neutrophils, the most abundant type of white blood cells in humans.

Ether-linked phosphatidyl­choline lipidomics analysis with Lipotype

Covered classes0
Approachuntargeted
Method
DeviceQ Exactive Orbitrap (280.000 Res)
Quantification
Delivery time2-6 weeks
Lipidomics data
Figuresincluded

ABOUT LIPOTYPE

Lipotype logo with Claim, 600 dpi

Lipotype is the leading lipidomics service provider for industry and academia. Order your service, send your samples, get your data.

Request analysis

You want to inquire lipid analysis for your project or ask questions about Lipotype Lipidomics? Please use the contact form below!

read more ➔