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How do I send dried blood spot samples for lipidomics analysis?
Contact us at service@lipotype.com to discuss your study requirements, sample numbers, compatible card types, and preparation guidelines before sending samples.
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How should dried blood spot samples be stored for lipidomics analysis?
DBS samples should be dried at room temperature and then stored frozen, ideally at -80°C, until analysis. While immediate cooling is not required at the moment of collection, cold storage is necessary to preserve lipid integrity prior to analysis.
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What are the advantages of DBS sampling over plasma for lipidomics studies?
DBS sampling requires only a finger prick, with no phlebotomy and no anticoagulants. This makes it ideal for decentralised clinical trials, longitudinal studies with frequent sampling, and large-cohort research where participant burden and logistics need to be minimised.
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Can dried blood spots be used for lipidomics research?
Yes. Dried blood spots are a validated matrix for quantitative lipidomics. Lipotype’s proprietary sample preparation method is specifically developed and validated for DBS, delivering the same accurate quantification in pmol and mol% as plasma-based lipidomics.
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How many lipid classes can be measured from a dried blood spot?
Lipotype’s DBS Lipid Panel quantifies 24 lipid classes from a single dried blood spot, compared to 16 from plasma. This includes cardiolipins, phosphatidylserines, and phosphatidylglycerols and other lipid classes that are not accessible from plasma samples.
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What is dried blood spot lipidomics?
Dried blood spot (DBS) lipidomics is the quantitative analysis of lipids from a small blood sample collected via finger prick onto a filter card. Unlike plasma lipidomics, DBS captures the full whole-blood lipidome, including lipid classes from blood cell membranes and mitochondria.
