Lipids in diabetes type 2 research

The Paul Langerhans Institute Dresden (PLID) tackles diabetes by applying lipidomics analysis form Lipotype.


Lipids and diabetes
The PLID frequently applies Lipotype Shotgun Lipidomics services for their molecular diabetes research to step by step reveal lipid-associated cellular processes. Their investigations lead to the definition of molecular lipid signatures that tell about the development on non-diabetic to diabetes type 2 and progression towards diabetes complications.

Furthermore, the PLID is a project partner of Lipotype within the RHAPSODY consortium, an IMI project combining new and existing data to refine diagnosis, promote prevention and support drug discovery for personalized management of diabetes.


About the PLID
In type 1 and type 2 diabetes, destroyed or impaired beta cells cause an elevated blood sugar level. PLID scientists are working on deciphering the mechanisms that lead to the destruction and/or functional impairment of beta cells and are also trying to develop new approaches to replace damaged or destroyed beta cells.

The PLID is a founding partner of the German Center for Diabetes Research (DZD).


Resources

1 – Multi-omics insights into functional alterations of the liver in insulin-deficient diabetes mellitus


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