De Camilli Lab
With its Shotgun Lipidomics technology, Lipotype delivered its one-of-a-kind, detailed, quantitative information on lipid structure and composition of control and knockout cells for selected LTPs and of their purified plasma membranes.
These observations provided new insight into mechanisms controlling lipid homeostasis at the plasma membrane. This fruitful collaboration between the De Camilli Lab and Lipotype demonstrates the power of lipid analysis in advanced cell biology research.
We study mechanisms underlying the dynamics and traffic of intracellular membranes, with emphasis on membrane transport reactions involved in neurotransmission. A major long-term goal is to advance the understanding of nervous system function in health and disease. We also exploit the unique structural and functional features of synapses to learn about general principles in membrane biology.
Y Saheki, X Bian, CM Schauder, Y Sawaki, MA Surma, C Klose, F Pincet, KM Reinisch, P De Camilli