CASE STUDY

Blood plasma lipids in diet intervention studies

Prof. Pfeiffer, CHARITÉ and German Institute of Human Nutrition (DIfE)

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Professor Andreas Pfeiffer, Director Endocrinology at Charité, Berlin and Head of the Department of Clinical Nutrition at the German Institute of Human Nutrition (DIfE) investigates the role of nutrient-dependent factors in the pathogenesis of major diseases of industrialized countries (e.g. obesity, diabetes mellitus, and the metabolic syndrome).The team of Professor Pfeiffer was interested in determining the effects of dietary interventions on the lipidome of human blood plasma.

With its Shotgun Lipidomics Technology, Lipotype delivered its one-of-a-kind, detailed, quantitative information on lipid structure and composition, revealing dietary effects on the global lipid composition of human plasma and how hereditary factors influence the lipid metabolism. This fruitful collaboration between Professor Pfeiffer and Lipotype demonstrates the power of lipid analysis in nutritional research.

About Professor Pfeiffer/Charité, Berlin and German Institute of Human Nutrition (DIfE)

Prof. Pfeiffer treats patients at the Medical Department of Endocrinology, Diabetes and Nutritional Medicine of the Charité Berlin (Campus Benjamin Franklin). A better understanding of the mechanisms eliciting the metabolic syndrome will provide a key for targeted strategies of prevention.

 

Reference
Heritability and responses to high fat diet of plasma lipidomics in a twin study – Scientific Reports, 2017

T Frahnow, MA Osterhoff, S Hornemann, M Kruse, MA Surma, C Klose, K Simons, AFH Pfeiffer